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KMID : 1130320100530020239
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Korean Journal of Pediatrics
2010 Volume.53 No. 2 p.239 ~ p.243
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High-dose caspofungin salvage in a very-low-birth-weight infant with refractory candidemia
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Seo Eun-Sun
Kim Byung-Guk
Kim Sung-Mi
Park Geun-Hwa
Jung Hye-An
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Abstract
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Candidiasis is one of the most common causes of late-onset infection among very-low-birth-weight infants (VLBW) in most neonatal intensive care units and is associated with significant morbidity and mortality. Standard therapy consists of the administration of amphotericin B, amphotericin B complex, and fluconazole. In many cases, candidiasis is not easily eradicated, despite the administration of these drugs. We report our experience of the addition of high-dose caspofungin to the conventional antifungal drugs in a VLBW infant with refractory candidemia.
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KEYWORD
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Candidiasis, Caspofungin, Infant, Very low birth weight
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